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Health & Fitness

Peptides Explained

by John Garrett

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Latest episodes

  • Vesugen and Vascular Aging: Interesting Biology or Overhyped Claim?

    October 7, 2026 · 16 min

    Vesugen is only three amino acids long: lysine, glutamate, and aspartate — KED. Yet it is promoted as a vascular bioregulator that may support endothelial health and even "rejuvenate" aging blood vessels. In this episode, John Garrett…

  • FLGR-242 Explained: Smarter Follistatin—or Unproven Hype?

    October 5, 2026 · 11 min

    FLGR-242 is being called a smarter, longer-acting follistatin. John examines the advertised construct, the activin-sparing and 19-day half-life claims, the difference between pathway evidence and product evidence, and why transformation…

  • Follistatin Explained: Can You Really Remove the Muscle-Growth Brake?

    September 30, 2026 · 10 min

    Follistatin can bind myostatin—one of the body's major restraints on skeletal-muscle growth. Animal studies are dramatic, and small human gene-therapy studies have produced encouraging signals in serious muscle disease. But is a vial…

  • Glutathione: The "Master Antioxidant" — or Master Marketing?

    September 28, 2026 · 15 min

    Glutathione gets called the "master antioxidant," and the underlying biology really is important. But does that mean oral supplements, liposomal products or glutathione IVs deliver the sweeping detox, energy, immune and anti-aging benefits…

  • GLP-1 Split Dosing: This Is NOT Microdosing

    September 23, 2026 · 13 min

    For more information on Research Peptides go to PeptidesExplained.info/OfflinePeptides Is taking smaller GLP-1 doses multiple times per week actually "microdosing"? Not necessarily. This episode separates split dosing from true dose…

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  • Icotyde: The Oral Peptide That Could Change Medicine

    September 21, 2026 · 18 min

    Download The Peptide App at ThePeptide.App/Explained For more information on research peptides check out PeptidesExplained.info/OfflinePeptides A peptide…in a pill? Icotyde, or icotrokinra, is an FDA-approved oral peptide designed to…

  • Why Your Favorite Peptides May Never Get a Big Human Trial

    September 16, 2026 · 17 min

    If BPC-157, TB-500, KPV, MOTS-C and similar peptides are so interesting, why don't we have giant randomized human trials? This episode looks at the less dramatic—and more important—answer: clinical trials require a sponsor, regulatory…

  • The Hollywood Trinity Stack: What Happened When I Tried It

    September 14, 2026 · 19 min

    Download The Peptide App @ ThePeptide.App/Explained For more info on research peptides visit PeptidesExplained.info/OfflinePeptides John Garrett shares his N=1 experience with the so-called "Trinity Stack"—established TRT, retatrutide…

  • SNAP-8: Is "Botox in a Bottle" Real?

    September 9, 2026 · 15 min

    SNAP-8 is a synthetic cosmetic octapeptide marketed for expression lines and frequently called "Botox in a bottle." John Garrett, RN, breaks down the SNAP-25 and SNARE-complex mechanism, the difference between topical SNAP-8 and injected…

  • GLP-1 Microdosing: Smart Strategy or the Next Wellness Fad?

    September 7, 2026 · 24 min

    Visit peptidesexplained.info for more info and resources For more info on research peptides check out PeptidesExplained.info/OfflinePeptides or email John at john@peptidesexplained.info What exactly is GLP-1 microdosing? Depending on…

  • Thymalin vs Thymogen: Can Thymus Peptides Reverse Immune Aging?

    September 2, 2026 · 15 min

    Can a peptide reverse age-related immune decline? Thymalin and Thymogen are often discussed together, but one is a complex calf-thymus extract and the other is the defined dipeptide Glu-Trp. John Garrett explains thymic involution, T-cell…

  • What Is Pinealon? Brain Aging, Neuroprotection, and the Evidence

    August 31, 2026 · 22 min

    Check out The Peptide App here: thepeptide.app/explained What is Pinealon, and does this three-amino-acid peptide really protect the aging brain? Pinealon—also called EDR or Glu-Asp-Arg—is a synthetic tripeptide associated with the…

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About the show

Peptides Explained breaks down the most talked-about peptides and GLP-1 medications in health, fitness, and longevity — including semaglutide, tirzepatide, BPC-157, TB-500, and more. Hosted by Registered Nurse John Garrett, this podcast explains how these compounds work, why they're popular, what the research shows, and the real risks and side effects — all in plain language. No bro science. No hype. Just clear, foundational education. For informational purposes only. Not medical advice. For Research Peptides; Offlinepeptides.com/ref/johngarrett/ https://www.skool.com/peptides-explained-15