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Two guys talking **it - A Gastroenterology and Hepatology podcast
by A/Prof Jon Segal and Dr James Haridy
Today: #125 in Health & Fitness, Brazil on our combined chart.
Chart positions today · South Africa
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Ranking history · South Africa
No ranking history for this show in South Africa over the last 7 days.
Latest episodes
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#14: Professor Nick Talley: Dyspepsia, Duodenums and the Trouble With "Functional"
August 9, 2026 · 49 minProfessor Nick Talley has spent 35 years building the field of neurogastroenterology, and he'd like us all to stop saying "functional". He is one of the global top medical researchers, a distinguished Australian gastroenterologist, and…
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#13: Jon and James - GLP-1s: From Lizard spit to liver fibrosis
June 12, 2026 · 42 minWe're back for Season 2, and Jon and James kick things off with one of their favourite topics: Incretin mimetics. The gut is the biggest endocrine organ in the body, and the data in steatotic liver disease is now as good as anything we…
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#12: Season 2 Trailer
June 8, 2026 · 2 minWe're back. After a longer-than-planned hiatus involving life, work, and the general chaos of being two busy clinicians: Two Guys Talking $#it is returning for Season 2. The spark? Jon got stopped in a hospital corridor by a non-gastro…
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#11: A/Prof Elliot Tapper - Liver legends, lies and lactulose
July 29, 2025 · 57 minToday we had the privilege of talking to a true superstar in the world of Hepatology. Elliot B. Tapper MD is an Associate Professor in the Division of Gastroenterology and Hepatology at the University of Michigan. He is Academic Chief of…
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#10: A/Prof Gianluca Ianiro and Dr Benjamin Mullish - The gut microbiome in health and disease
July 9, 2025 · 1 hr 3 minToday we’re talking bugs, bowels, and breakthroughs with A/Prof Gianluca Ianiro and Dr. Ben Mullish, two microbiome maestros who make poo science strangely fascinating. A/Prof Gianluca Ianiro is an Associate Professor of Gastroenterology…
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#09: A/Professor Emma Halmos & Dr CK Yao - Food is Medicine.. or is it?
June 5, 2025 · 56 minToday we welcome two world-leading dietitians to talk all things diet in IBD and IBS.... A/Prof Emma Halmos is a senior research dietitian at Monash University and the Alfred Hospital. Her scientific achievements have had a major impact…
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#08: Professor Gideon Hirschfield - The Art and Science of PSC and Autoimmune Hepatitis
April 28, 2025 · 1 hr 6 minSummary Dr Gideon Hirschfield is a leading expert in autoimmune liver diseases, including PSC, PBC, and autoimmune hepatitis. He’s helped shape how these conditions are understood and managed around the world, combining cutting-edge…
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#07: Dr Simon Gabe - Rebuilding the gut: Intestinal rehabilitation
April 7, 2025 · 1 hr 3 minThis is a really special episode with an incredible doctor (Jon says "the best clinician I have ever met"). Today we welcome Dr Simon Gabe, an internationally renowned expert in intestinal rehabilitation. Dr Simon Gabe is a consultant in…
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#06: ECCO Takeaways with Dr Beatriz Gros
March 23, 2025 · 1 hr 4 minJon and James welcome Dr Beatriz Gros, a leading expert in inflammatory bowel disease (IBD). They discuss key findings from the recent European Crohn's and Colitis Conference in 2025. Dr. Beatriz Gros (X: @bealoquebea Instagram…
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#05: A/Professor Jason Tye-Din - Coeliac Disease unpacked: Diagnosis, treatment and emerging approaches
February 8, 2025 · 58 minWe very excited about the episode today! We are joined by A/Professor Jason Tye-Din - a leading expert in coeliac disease and immune-mediated gut disorders. He is Coeliac labratory head at the Walter and Eliza Hall Institute of Medical…
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#04: Professor Alex Ford - Navigating disorders of gut-brain interaction and IBS
January 22, 2025 · 1 hr 11 minProfessor Alex Ford is a renowned researcher in Gastroenterology, specializing in Disorders of Gut-Brain Interaction (DGBIs). Based at the University of Leeds, he has authored numerous high-impact studies on conditions like irritable bowel…
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#03: Our best of 2024 in Gastroenterology and Hepatology
January 15, 2025 · 43 minEvery podcast is incomplete without a 'best of' episode from the previous year. In this episode Jon and James talk about their big learnings / seminal papers / themes of 2024 in Gastroenterology and Hepatology. We wish we could have…
About the show
“Two Guys Talking $#it” is a podcast where two Gastroenterologists break down complex topics into engaging, educational, and occasionally humorous conversations. From liver health to gut microbiota and everything in between, A/Professor Jonathan Segal and Dr James Haridy deliver insights, share the latest research, and discuss clinical pearls with the odd guest in tow.
Comments, suggestions, questions please contact us on twitter @2guystalkingit or leave a comment below..