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Health & Fitness

The Matt Walker Podcast

by Dr. Matt Walker
MedicineHealth & FitnessScience

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Latest episodes

  • #157 - Sleep Walking and Talking

    October 26, 2026 · 28 min

    Matt examines the world of parasomnias this week, focusing on sleepwalking and sleep talking. Dispelling the myth that sleep is a simple on/off switch, he explains how these behaviors reveal a brain that is simultaneously awake and asleep…

  • #156 - Smell and Memory

    October 19, 2026 · 29 min

    Examining the "Proust phenomenon," Matt reveals how smell acts as a direct portal to our past. Unlike sight or hearing, olfaction bypasses the brain's typical sensory relay and connects directly to memory centers like the hippocampus. This…

  • #155 - Sleep & Nature's Call

    October 12, 2026 · 28 min

    Matt explores nocturia, the clinical condition of waking at night to urinate, challenging the assumption that the bladder is solely at fault. Using a measuring jug to illustrate bladder capacity, Matt explains that the bladder is usually…

  • #154 - Sleep and Cortisol

    October 5, 2026 · 29 min

    Delving into the science of cortisol, Matt debunks its social media reputation as a toxic villain. He explains how this essential hormone actually regulates metabolism, immunity, and survival. He also unpacks the healthy "Cortisol…

  • #153- Sleeping in an MRI Machine

    September 28, 2026 · 25 min

    Today’s episode explores how scientists study the sleeping brain inside a roaring, 111-decibel MRI scanner. Despite the extreme noise and discomfort, researchers use sleep deprivation, earplugs, and clever audio-filtering tricks to capture…

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  • #152 - The Brain on Music

    September 21, 2026 · 28 min

    Exploring the profound link between the brain and music, Matt begins by tracing musical expression back 40,000 years to a vulture bone flute, arguing that music evolved as a "social glue" to foster group bonding. He explains the…

  • #151 - The Geography of Sleep

    September 14, 2026 · 24 min

    Matt breaks down the conflict between wall clocks and our biological rhythms, explaining how latitude and longitude dictate our rest. Latitude alters seasonal daylight and melatonin - though artificial light mutes this natural cycle - and…

  • #150 - The Neuroscience of Déjà Vu

    September 7, 2026 · 32 min

    Matt digs into the neuroscience of déjà vu, reframing it as a sign of a healthy brain performing real-time error correction. Using a "doorman" (familiarity) vs. "concierge" (recollection) analogy, Matt explains how memory systems misfire…

  • The Night Ferryman: A Sleep Story Read by Matt Walker

    August 31, 2026 · 35 min

    Join Matt for a serene excursion across a valley lake under the cover of night. After finding a comfortable position and centering your breath, you will step onto the deck of a weathered ferry. Marcus, the pilot, unties the lines, steering…

  • #149 - The 11 largest Sleep Myths

    August 24, 2026 · 27 min

    Debunking 11 sleep myths, Matt begins by explaining that the brain remains active, not "off," during rest. He goes on to argue that 7-9 hours of sleep is vital and warns that "adapting" to less is a delusion that masks performance deficits…

  • #148 - Psychedelics for Mental Health

    August 17, 2026 · 32 min

    Matt delves into how psychedelics like psilocybin and LSD quiet the "Default Mode Network" to boost neuroplasticity. He describes these molecules as a "crowbar" that allows therapy to break deep-seated patterns of depression and reorganize…

  • #147 - Does Sleep Really Clean Your Brain?

    August 10, 2026 · 25 min

    Matt explores the brain's secret plumbing, a waste-clearance network once ignored for over a century. He explains how the glymphatic system flushes metabolic toxins like amyloid-beta during sleep. This "night shift" allows fluid to cleanse…

Full episode archive on Apple Podcasts →

About the show

The Matt Walker Podcast is all about sleep, the brain, and the body. Matt is a Professor of Neuroscience at the University of California, Berkeley. He is the author of the book, Why We Sleep and has given a few TED talks. Matt is an awkward British nerd who adores science and the communication of science to the public.