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The Lancet Gastroenterology & Hepatology in conversation with

by The Lancet Group

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Latest episodes

Helen Jarvis on the role of primary care in response to the global liver disease syndemic

October 13, 2026 · 21 min

How can we strengthen primary care-led liver health care? In this episode, we chat with Dr Helen Jarvis who led the recently published Commission on the role of primary care in response to the global liver disease syndemic. Click here to…
Pere Ginès on long-term liver stiffness measurement as a screening tool for liver fibrosis

September 11, 2026 · 19 min

Could repeated liver stiffness measurement offer a practical approach to population-based liver fibrosis screening? In this episode, we speak with Pere Ginès about the LiverScreen study, which analysed changes in liver stiffness over time…
Frank Ruemmele on a trial of cyclic exclusive enteral nutrition versus partial enteral nutrition to maintain remission in paediatric Crohn's disease

August 13, 2026 · 23 min

In children with Crohn’s disease who achieve remission through exclusive enteral nutrition, what's the optimal dietary therapy to maintain remission without the use of medication or surgery? Frank Ruemmele (Université Paris Cité) talks…
Aleksander Krag on the utility of PEth for subclassifying individuals at risk of steatotic liver disease

February 23, 2026 · 20 min

Steatotic liver disease labels hinge on alcohol intake, but self-report is often inaccurate. In this episode, Aleksander Krag (Odense University Hospital) discusses a large Danish study using phosphatidylethanol (PEth), a direct blood…
Dina Kao on a trial of lyophilised sterile faecal filtrate versus lyophilised conventional donor stool for recurrent Clostridiodes difficile infection

November 28, 2025 · 16 min

Can bacteria-free, sterile faecal filtrate match conventional faecal microbiota transplantation for recurrent C difficile infection? Dina Kao (University of Alberta) unpacks a landmark multicentre trial that tested this hypothesis, and we…

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Premysl Bercik on a double-blind crossover trial of gluten and wheat in IBS

November 20, 2025 · 16 min

Do wheat or gluten trigger IBS symptoms? We spoke to Premysl Bercik about a randomised, double-blind, sham-controlled crossover trial that challenged adults with IBS—who reported benefit from a gluten-free diet—with wheat, gluten, or a…
Julia Mayerle on the validation of plasma multimetabolite signatures for patients at risk of or with suspected pancreatic ductal adenocarcinoma

June 19, 2025 · 27 min

Can a multi-metabolite blood test improve early pancreatic cancer detection? We spoke to Julia Mayerle about the METAPAC study, which sought to validate the ability of plasma metabolic signatures to find resectable tumors and reduce…
Salvatore Piano on the global epidemiology of acute kidney injury in hospitalised patients with decompensated cirrhosis

April 9, 2025 · 19 min

How does acute kidney injury presentation and management differ globally for patients hospitalised with cirrhosis? We spoke to Salvatore Piano, corresponding author of the landmark International Club of Ascites GLOBAL AKI study, about…
John Chia on the ASCOLT trial of adjuvant aspirin for colorectal cancer

March 6, 2025 · 13 min

John Chia discusses the results of the ASCOLT trial, which explored the effect of aspirin after completion of standard adjuvant therapy for patients with colorectal cancer. Read the full article: https://www.thelancet…
Hannes Hagström on screening for advanced liver fibrosis alongside retina scanning in people with type 2 diabetes

January 10, 2025 · 21 min

Hannes Hagström discusses a study investigating the feasibility of screening for advanced liver fibrosis alongside retina scanning in people with type 2 diabetes. Read the full article: https://www.thelancet.com/journal…
Cathy Lu on intestinal ultrasound for assessing and monitoring Crohn’s disease small bowel strictures

December 12, 2024 · 11 min

Cathy Lu (University of Calgary) discusses a consensus statement on the use of intestinal ultrasound for assessing and monitoring small bowel strictures in Crohn's disease. Read the full article: https://www.thelancet.c…
Peter De Cruz on the PREDICT-UC trial of intensified versus standard dose infliximab for steroid-refractory acute severe ulcerative colitis

November 6, 2024 · 15 min

Peter De Cruz (University of Melbourne) discusses the PREDICT-UC trial of intensified versus standard dose infliximab induction therapy for steroid-refractory acute severe ulcerative colitis. Read the full article: http…

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About the show

Hugh Thomas, Deputy Editor at The Lancet Gastroenterology & Hepatology, in conversation with the journal’s authors, explores their latest research and its impact on people’s health, healthcare, and health policy.A monthly audio companion to the journal, this podcast covers a broad range of topics, from predicting clinical outcomes in NAFLD to immunosuppressant withdrawal in patients with Crohn’s disease, the primary antibiotic resistance of Helicobacter pylori to surgical versus non-surgical management of malignant bowel obstruction, and more.