Less of You: Life on Semaglutide & Tirzepatide podcast artwork
Health & Fitness

Less of You: Life on Semaglutide & Tirzepatide

by Eva Sheie & Kami Gamlem
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Latest episodes

  • Halloween Costumes Fit Me Now?

    October 23, 2026 · 45 min

    Two trips to Spirit Halloween this month, and Eva realizes for the first time in her adult life she can fit into everything instead of eyeing the inflatable dinosaur costume.  The scale reads 179, a number that hasn't started with a one…

  • It’s My Face. Thanks.

    September 25, 2026 · 26 min

    Kami is five days into recovery from a balloon sinuplasty and turbinate reduction, and it has been brutal — she’s too congested to wear her CPAP, she can’t use her mouth guard while mouth-breathing all night, and she’s up every hour…

  • Courtroom Wins, Evil Clowns, Pink Shoelaces

    September 18, 2026 · 41 min

    Eva marched a Stephen King-grade demon clown costume up to the register in a store for kids — and when the manager disagreed that it didn’t belong there, she bought $50 Boden sneakers  out of spite for the place. Weeks later, her…

  • The Scale Is Finally Moving Again

    September 4, 2026 · 36 min

    Eva hadn't budged from 186 for a year and a half — until she stepped on it this week and saw 180, a number she hasn't seen in ages, ice cream summer in Washington included. Kami has her own update: three pounds down in her fourth week of…

  • Do I look better yet?

    August 21, 2026 · 32 min

    Three weeks after her Halo resurfacing, Eva decides to take the opportunity to have a Junera laser treatment, a new technology that treats the skin from within to tighten the face and neck from the inside.  On the morning before heading…

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  • Replacing The Microwave (Also Known As The Micro-Wah-Vay)

    August 14, 2026 · 27 min

    After an important discussion about the microwave (also known as the micro-wah-vay), we theorize that GLP-1s are basically commoditized now.  Meanwhile, to fix the microwave door, Eva's husband drove actual screws through it (that’s not…

  • I Did Halo Laser Resurfacing On My Way to a Dance Recital

    August 7, 2026 · 30 min

    After Eva went in for Halo laser resurfacing with a friend (who happens to be one of the best in the world), she walked out looking horrifying (according to the 8 year old) then drove straight to a dance recital tearing a cooling mask in…

  • We're Back, and We Found a Cheaper Way to Get Your Meds

    July 31, 2026 · 46 min

    After an accidental three-and-a-half-month hiatus, we are back with updates and committing to every week. We catch up on  kids, summer camps, GLP-1 dosing and pricing, HRT and perimenopause, peptides, and one genuinely scary night at the…

  • Why you shouldn’t go off meds

    March 27, 2026 · 31 min

    Kami goes off her GLP-1, stops her thyroid meds, and gains back 25 lbs. After 3 months of Eva being angry for no reason, it turns out she just needs hormones. Eva + Kami are two old-ish moms with little kids confronting our reasons for…

  • The Dryer Shrunk My Jeans

    January 9, 2026 · 29 min

    Kami runs out of weight loss meds during the holidays, gains 10 pounds, and blames the dryer for shrinking her clothes. Eva overschedules everything, battles inconsistent clothing sizes at fancy events, and gets unsolicited body size…

  • I took a 4 week break from semaglutide and here’s what happened

    November 14, 2025 · 37 min

    Eva gets ghosted in the middle of an important situation and spirals for a day. Kami stops her meds and finds out what it feels like to be hungry again after two years. Check out Murderland: Crime and Bloodlust in the Time of Serial…

  • You Want Fries With That?

    October 3, 2025 · 31 min

    After sewing a quilt on the floor, Kami’s back goes out. After kicking a dumbbell, her foot goes out too. New compounded meds including glycine and B12 make a noticeable dent in Eva’s persistent body aches. A 3-week pause in medication to…

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About the show

Eva + Kami are two old-ish moms confronting our reasons for being obese while losing weight on semaglutide and tirzepatide, and roasting our past selves. Sarcasm is our happy place. Follow us on Instagram @lessofyoupodcast.  After a friend (who is a plastic surgeon) talked Eva into starting semaglutide in February of 2023, she lost 70 pounds in 14 months, alternating between long stretches of being stalled at the same weight and consistent but slow weight loss.  Chasing a lifelong dream to being considered just overweight and not obese by the BMI calculator, after 14 months Eva switched to tirzepatide to try and reach a goal that still seems just out of reach.   A prolific eater of her feelings, Kami was tired of being uncomfortable and when she heard through a mutual friend how semaglutide had changed Eva’s life, she found a trusted medical weight loss provider and took the first step.  As Kami starts her life on semaglutide, Eva adjusts to a world with less food noise and figures out how to let go of the crippling negative self-talk.  On each episode, we connect on how our lives are changing in real time as semaglutide and tirzepatide help us be smaller people, and try to answer the bigger question for ourselves:  When there’s less of you, what is left?