This Week in Neuroscience
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Latest episodes
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Arc, tau, and Alzheimer's
September 29, 2026 · 1 hr 9 minJason Shepherd joins TWiN to discuss the work in his laboratory showing that Arc protein plays a role in intercellular transmission of tau protein, which becomes hyperphosphorylated and misfolded, a major histopathological hallmark of…
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Plastic astrocyte networks with Melissa Cooper
July 30, 2026 · 1 hr 6 minMelissa Cooper joins TWiN to discuss her discovery that astrocytes connect specific brain regions through plastic networks. Hosts: Vincent Racaniello and Tim Cheung Guest: Melissa Cooper Subscribe (free): Apple Podcasts, Google…
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The price of a bigger brain
June 25, 2026 · 1 hr 27 minTWiN unpacks a striking paradox, that the very cell divisions that built the human brain's most advanced layers also put them at greatest risk, and how a dedicated DNA repair pathway saves them. Hosts: Vincent Racaniello, Vivianne…
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TWiN 72: What cesarean babies miss
June 1, 2026 · 1 hr 9 minTWiN explains the finding that vaginal microbiota transfer ameliorates cesarean-associated neurodevelopmental deficits in mice via synthesis of a sphingosine derivative on neonatal skin. .Hosts: Vincent Racaniello, Vivianne Morrison, and…
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Psychedelics rewire the brain from within
April 29, 2026 · 1 hr 31 minTWiN explains the finding that activation of intracellular, not plasma membrane, serotonin 2A receptors is responsible for the plasticity-promoting and antidepressant-like properties of psychedelic compounds. Hosts: Vincent Racaniello…
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Unraveling the axon wrap
March 17, 2026 · 1 hr 19 minTWiN explains the role of a ubiquitin ligase component in regulating the sheathing of multiple axons by Schwann cells. Hosts: Vincent Racaniello, Vivianne Morrison, and Tim Cheung Subscribe (free): Apple Podcasts, Google Podcasts, RSS…
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Fibromyalgia and the microbiome
March 5, 2026 · 1 hr 11 minTWiN explains a study which showed that transplanting gut microbiota from women with fibromyalgia into mice induces pain, as well as phenotypes commonly observed in patients, such as immune activation, metabolomic changes, and reduced skin…
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Firewall for the brain
January 27, 2026 · 1 hr 14 minTWiN explores the use of speech brain-computer interfaces to restore communication to people with paralysis, and reveals strategies for protecting private inner speech. Hosts: Vincent Racaniello, Vivianne Morrison, and Tim Cheung…
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Interpreting situation-specific facial signals
December 24, 2025 · 1 hr 31 minTWiN explores how theta phase shifts mediate contextual perception of facial expressions during everyday social interactions. Hosts: Vincent Racaniello, Vivianne Morrison, and Tim Cheung Subscribe (free): Apple Podcasts, Google…
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Neuroscience of overeating
November 26, 2025 · 1 hr 24 minTWiN reviews the underlying neurobiological mechanisms of overeating and obesity, the role of the hypothalamus and reward systems in controlling food intake and energy balance, and how dysregulation in these systems leads to overeating…
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Air pollutants promote dementia
November 4, 2025 · 1 hr 37 minTWiN explains epidemiological data showing that exposure to air pollution was associated with an increased risk of developing Lewy body dementia, and nasal administration of air pollution in mice led to brain atrophy and impaired cognition…
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How the brain decides what we see
October 8, 2025 · 1 hr 14 minTWiN explains how visual neurons show functional flexibility by selectively responding to subsets of inputs representing attended objects while ignoring those conveying information about irrelevant objects. Hosts: Vincent Racaniello…

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