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Health & Fitness

Mastering Nutrition

by Chris Masterjohn, PhD

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Latest episodes

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  • Mitochondria: Why They Control Everything in Human Health

    December 4, 2025 · 1 hr 43 min

    Mitochondria govern everything. Watch this with the slides here: https://www.youtube.com/watch?v=mED1_L3wZbc Mitochondria convert your food to usable energy in the form of ATP, which is used to produce, maintain, repair, distribute, and…

  • SSRI Withdrawal Is Mitochondrial Dysfunction

    November 23, 2025 · 1 hr 29 min

    Chris Masterjohn, PhD, Founder and Scientific Director of mito.me, explains why SSRI withdrawal is mitochondrial dysfunction and what to do about it. This is not medical advice, diagnosis, or treatment.  29 million Americans and about…

  • How Lactate Alkalinizes Your Muscles

    September 6, 2024 · 1 hr 35 min

    For a long time, most people believed that when we exercise, our muscles make lactic acid, this acidifies the muscles, and the acidity contributes to contractile failure, fatigue, and delayed-onset muscle soreness. Some people still…

  • D-Lactate: Groundbreaking Research No One Is Talking About

    July 31, 2024 · 1 hr 30 min

    D-lactate is commonly stated to be exclusively a microbial metabolite.  This is found in assumptions within the medical literature for decades even when it was long-known to be false.  While D-lactate is indeed made by bacteria…

  • Handling Creatine Side Effects

    July 12, 2024 · 2 min

    In this podcast we cover elevated creatinine, insomnia, cramps constipation, water retention, hair loss, irritation and anger, lightheadedness during lifting, bloating, aggravation of restless leg syndrome, irritation of asthma, bloody…

  • Your Cells Are Starving For Creatine

    July 12, 2024 · 29 min

    Creatine is like your second mitochondria. Or, the mitochondria's chief of staff. Or its co-pilot. Your mitochondria make ATP so you can see clearly, hear accurately, digest your food, power your brain, show off your your shiny skin, lift…

  • Is Whole Food Vitamin C Really Different? | Masterjohn Q&A Files #330

    December 18, 2023 · 23 min

    Question: Is whole food vitamin C superior to natural because it is part of a tyrosinase complex? Short Answer: Vitamin C is nearly ubiquitously distributed in plant tissues, and is never bound to any enzyme as a structural complex…

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About the show

Welcome to the Mastering Nutrition podcast. Mastering Nutrition is hosted by Chris Masterjohn, a nutrition scientist focused on optimizing mitochondrial health, and founder of BioOptHealth, a program that uses whole genome sequencing, a comprehensive suite of biochemical data, cutting-edge research and deep scientific insights to optimize each person's metabolism by finding their own unique unlocks. He received his PhD in Nutritional Sciences from University of Connecticut at Storrs in 2012, served as a postdoctoral research associate in the Comparative Biosciences department of the University of Illinois at Urbana-Champaign's College of Veterinary Medicine from 2012-2014, served as Assistant Professor of Health and Nutrition Sciences at Brooklyn College from 2014-2017, and now works independently in science research and education.