Science

From First Principles

by Krishna Choudhary and Lester Nare

Science

Today: #21 in Science on our combined chart.

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Chart positions today · United States

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#21

#36#28#36#35 Pulse 34

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Ranking history · United States

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Latest daily rankings: Oct 21. New rankings will appear after the next update.

Position on the Science combined chart over the last 7 days. Toggle platforms to compare their positions. Lower rank numbers are better.

View as table

Date	Combined Rank	Apple Podcasts	Spotify	Pocket Casts	Castbox
Oct 21	#21	#36	#28	#35	#36
Oct 20	#20	#35	#27	#35	#35
Oct 19	#20	#33	#27	#35	#32
Oct 18	#20	#33	#27	#30	#30
Oct 17	#18	#29	#25	#29	#28
Oct 16	#18	#27	#25	#26	#26
Oct 15	#18	#30	#22	#29	#29

Latest episodes

Nobel Prize 2026: The Science Gets Stranger

October 16, 2026 · 1 hr 59 min

Can light restore aspects of sight? Can recalling a cold experience change an animal's metabolism? And what can ghost particles and mirror-image molecules tell us about the universe? Lester Nare and Krishna Choudhary follow up on our 2026…
Nobel Prize in Chemistry 2026 Explained: Mirror Molecules (EP 63)

October 7, 2026 · 1 hr 21 min

Why does life favor one molecular mirror image? The 2026 Nobel Prize in Chemistry honors Henri B. Kagan and Kenso Soai for nonlinear effects and autocatalysis in asymmetric organic synthesis. Lester Nare and Krishna Choudhary unpack the…
Nobel Prize in Physics 2026 Explained: IceCube & Neutrinos (EP 62)

October 6, 2026 · 1 hr 2 min

Why build a telescope inside a billion tons of Antarctic ice? The 2026 Nobel Prize in Physics recognizes Francis Halzen's work on IceCube and the discovery of high-energy neutrinos from the cosmos. In Episode 62 of From First Principles…
Nobel Prize in Medicine 2026 Explained: Optogenetics (EP 61)

October 5, 2026 · 1 hr 11 min

How do you prove what a brain cell actually does? The 2026 Nobel Prize in Medicine celebrates a remarkable answer: give cells a light-sensitive protein, then switch their activity on or off with light. In Episode 61 of From First…
2026 Nobel Prize Predictions: Medicine, Physics & Chemistry (EP 60)

October 3, 2026 · 41 min

Who could win the 2026 Nobel Prizes? From the science behind Ozempic to quantum interference and droplets inside living cells, Lester Nare and Krishna Choudhary make their picks for Medicine, Physics and Chemistry, and explain the…

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Golden Goose Awards 2026: The Science Behind the Winners (Part 1) (EP 59)

September 29, 2026 · 2 hr 7 min

What connects a noise complaint, holiday lights seen from space, and the physics of a coffee stain? Three unexpected paths from basic research to discoveries with real-world impact. Krishna Choudhary and Lester Nare explore the science…
What OpenAI Actually Did to Navier-Stokes (EP 58)

September 24, 2026 · 4 hr 9 min

What does it mean to solve an equation that describes almost every fluid around us, from the air over a wing to the water swirling down a drain? In Episode 58 of From First Principles, Lester Nare and Krishna Choudhary build the…
What’s Next in Science? Nobel Prizes, Space Missions & More (EP 57)

September 14, 2026 · 1 hr 4 min

What science should you be watching this fall? From Nobel Prize season to NASA’s Roman Space Telescope, Mars’ moons and Mercury, Lester Nare and Krishna Choudhary take a relaxed tour of the discoveries and missions on their radar. In…
The Yak Mutation That Could Help Repair the Brain (EP 56)

September 7, 2026 · 1 hr 36 min

What can a yak living thousands of meters above sea level teach us about repairing the human brain? In Episode 56 of From First Principles, Lester Nare and Krishna Choudhary break down a new Neuron paper that traces an evolutionary…
Why Spin Qubits Will Win the Quantum Race (Part 2) (EP 55)

August 31, 2026 · 3 hr 46 min

Which quantum computer will actually scale? In Part 2 of our quantum computing deep dive, Lester Nare and Krishna Choudhary move from theory to hardware—comparing superconducting qubits, trapped ions, neutral atoms, and silicon spin qubits…
How Quantum Computing Actually Works (Part 1) (EP 54)

August 20, 2026 · 2 hr 11 min

Quantum computers do not simply “try every answer at once.” So what do they actually do—and why have governments and technology companies spent billions trying to build them? In Part 1 of our two-part quantum computing deep dive, Lester…
What Claude Actually Did to the Riemann Hypothesis (EP 53)

August 14, 2026 · 1 hr 47 min

Claude did not solve the Riemann Hypothesis. But what it actually did may be one of the clearest examples yet of how rapidly AI systems are changing the way difficult mathematics can be attacked. In Episode 53, Lester Nare and Krishna…

Full episode archive on Apple Podcasts →

About the show

From First Principles is a fast, funny, and rigorous breakdown of the biggest science stories of the week, hosted by Lester Nare and physicist Krishna Choudhary, PhD. We go past headlines into the actual mechanics: what happened, why it matters, and what everyone’s missing. Expect physics, space, AI, energy, biotech, and the occasional “wait… is that real?” story. If you’re curious, skeptical, and you like learning in public — you’re in the right place.