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by Andreessen Horowitz

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Latest episodes

How Startups are Fixing Healthcare Friction

June 25, 2025 · 24 min

What if the biggest lever for improving U.S. healthcare isn’t clinical, but operational? In this episode, recorded live at New York Tech Week, a16z General Partner David Haber speaks with Trey Holterman (Tennr) and Christophe Rimann…
What Comes After Mobile? Meta’s Andrew Bosworth on AI and Consumer Tech

April 24, 2025 · 33 min

For the past 20 years, consumer technology has been shaped by the same form factors: apps and touchscreens on smartphones. But advances in AI, wearables, and hardware could introduce an entirely new stack—creating a more agentic, adaptive…
Who Will Own the Internet? a16z’s Chris Dixon on AI and Crypto

February 21, 2025 · 33 min

Technology doesn’t grow in isolation—it evolves in waves. Just as mobile, cloud, and social shaped the internet of the past 20 years, so too could crypto, AI, and new hardware usher in an era of the internet that’s pro-innovation…
How AI Is Changing Warfare, with Anduril CEO Brian Schimpf

February 13, 2025 · 35 min

Anduril reimagined how startups can build software and hardware for the defense sector. Now, they're using AI to reimagine modern warfare. Speaking with a16z Growth General Partner David George, Anduril cofounder and CEO Brian Schimpf…
In The Vault: How AI is Powering Payments with Greg Ulrich

February 4, 2025 · 29 min

How does a company as massive as Mastercard decide where to deploy AI? Instead of centralizing every AI initiative, Mastercard operates under a “hub and spoke” model — balancing centralized AI leadership with decentralized innovation…

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How Jack Henry is Modernizing Banking Infrastructure

December 19, 2024 · 27 min

Most financial institutions still bank on software built before the internet, but Jack Henry's CTO, Ben Metz, is leading a quiet revolution to change that. Speaking with a16z General Partner Angela Strange, Metz shares how banks’…
Building a $20B+ Open Source Business with MongoDB's Eliot Horowitz

December 12, 2024 · 40 min

a16z Partner Seema Amble talks with MongoDB and Viam co-founder Eliot Horowitz about building sustainable open source software tools. From challenging Oracle to building the de facto cloud-based database management tool, Horowitz outlines…
How Zapier Became Profitable in 3 years and Scaled to $5B with Wade Foster

December 10, 2024 · 32 min

a16z Partner Seema Amble connects with Zapier co-founder Wade Foster about the company’s founding and GTM success utilizing a product-led growth (PLG) strategy. Chock-full of actionable insights, this episode explores Zapier’s product…
How Gusto Used Customer Input to Scale Growth with Tomer London

December 5, 2024 · 31 min

In this episode, a16z Partner Seema Amble chats with Tomer London, co-founder of Gusto, about establishing product-market fit and product discovery. London shares how Gusto, now valued at ~$10 billion with 300,000+ customers, identified…
How to Build a Thriving AI Ecosystem with Lisa Su, CEO of AMD

October 30, 2024 · 37 min

High-performance compute is the bedrock of generative AI, and if there’s anyone who knows about high-performance chips, it’s AMD CEO Lisa Su. In this wide-ranging conversation with a16z Operating Partner Bob Swan—himself formerly CEO of…
a16z Growth's David George on His Frameworks for Late-Stage Investing

October 15, 2024 · 59 min

Finding and backing companies that can reach escape velocity is the name of the game over here at a16z Growth—but picking those winners is far from easy. David George, head of the a16z Growth fund, sat down with the I/O podcast to discuss…
Why Human Data is Key to AI: Alexandr Wang from Scale AI

October 4, 2024 · 35 min

In this conversation with a16z general partner David George, Scale AI founder and CEO Alexandr Wang discusses the three pillars of AI—models, compute, and data—and how creating abundant data is core to the evolution of gen AI. With Scale’s…

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About the show

a16z Live is the place to listen to recorded live discussions and events featuring, hosted, or co-hosted by a16z partners (with outside voices too). As a reminder, all content posted here is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. Views expressed are those of the individuals and not the views of Andreessen Horowitz, please see a16z.com/disclosures for more. To learn more about the broader a16z Podcast network and shows, please visit a16z.com/podnetwork.