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In the Interim...

by Berry
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Latest episodes

  • Clinical Trial Arenas: Direct Communication to Patients

    September 28, 2026 · 43 min

    In this episode of "In the Interim…", Dr. Scott Berry recounts a presentation he gave to the Speak Foundation, a patient organization focused on limb-girdle muscular dystrophy and makes the case for master protocols directly to the…

  • Science Coaching With Alun Bedding

    September 21, 2026 · 45 min

    In this episode of "In the Interim…", Dr. Scott Berry talks with Dr. Alun Bedding, a professional certified coach and statistician who spent decades in pharmaceutical statistics, including as global head of statistical methods…

  • The CHIPS Trial: Bayesian Adaptive Trial in JAMA

    September 14, 2026 · 46 min

    In this episode of “In the Interim…,” Dr. Scott Berry talks with Dr. Roger Lewis, Dr. Anna McGlothlin, and Dr. Nick Berry — all co-authors on the CHIPS trial results recently published in JAMA (Spinella et al., August 2026) — about the…

  • NFL Study of CTE: The Issues

    September 7, 2026 · 39 min

    In this episode of "In the Interim…", Dr. Scott Berry examines three recent health-research headlines through a statistician's lens: an Adventist Health Study-2 analysis claiming eggs reduce Alzheimer's risk, an Emory University trial on…

  • Talkin' 'bout Sweet Time

    August 31, 2026 · 47 min

    In this episode of "In the Interim...", Dr. Scott Berry dissects prevailing concepts of “clinically meaningful difference” in clinical trials focusing on progressive diseases. Through detailed examples from pancreatic cancer (Ben Sasse…

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  • Mammograms: Death Threats, Hillary Clinton and Lead-Time Bias

    August 17, 2026 · 1 hr 6 min

    In this episode of "In the Interim…", Dr. Don Berry provides a detailed account of co-chairing the 1997 NIH consensus development conference on mammography for women in their 40s. His conversation with Dr. Scott Berry covers the…

  • REMAP-CAP Results: Oseltamivir in Critically-Ill Influenza Patients

    August 10, 2026 · 52 min

    In this episode of "In the Interim…", Dr. Scott Berry speaks with Dr. Srinivas Murthy, Dr. Thomas Hills, and Dr. Lindsay Berry about the REMAP-CAP trial results on oseltamivir in critically ill influenza patients. The trial used a Bayesian…

  • ICECAP: The Results

    August 5, 2026 · 55 min

    In this episode of "In the Interim…", Dr. Scott Berry leads a comprehensive discussion of the ICECAP trial results with four Principal Investigators: Dr. Will Meurer (Professor, Emergency Medicine and Neurology, University of Michigan…

  • Failure of the Proportional Odds is the Result

    August 3, 2026 · 40 min

    In this episode of "In the Interim…", Dr. Scott Berry and Dr. Elizabeth Lorenzi systematically examine the analytic pitfalls in recent acute ischemic stroke trials, especially the implications of violating the proportional odds assumption…

  • Adaptive Design Actions Matrix

    July 27, 2026 · 31 min

    In this episode of "In the Interim…", Dr. Scott Berry challenges the widely held belief that any interim look at trial data obligates an alpha adjustment. By constructing a two-by-two matrix: interim data (positive/negative) and adaptive…

  • A Visit With Tim Berry

    July 20, 2026 · 44 min

    In this episode of "In the Interim…," Dr. Scott Berry interviews Tim Berry, co-founder of Blend360, detailing a career that demonstrates the practical application of statistical and analytical methods within large-scale business…

  • Fairness in Soccer and Clinical Trials

    July 13, 2026 · 35 min

    In this episode of "In the Interim...", Dr. Scott Berry investigates the practical meaning of fairness by connecting a controversial World Cup soccer ruling to foundational questions in clinical trial statistics. Scott scrutinizes FIFA’s…

Full episode archive on Apple Podcasts →

About the show

A podcast on statistical science and clinical trials. Explore the intricacies of Bayesian statistics and adaptive clinical trials. Uncover methods that push beyond conventional paradigms, ushering in data-driven insights that enhance trial outcomes while ensuring safety and efficacy. Join us as we dive into complex medical challenges and regulatory landscapes, offering innovative solutions tailored for pharma pioneers. Featuring expertise from industry leaders, each episode is crafted to provide clarity, foster debate, and challenge mainstream perspectives, ensuring you remain at the forefront of clinical trial excellence.