Health & Fitness

Endocrine Feedback Loop

by Endocrine Society

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Latest episodes

EFL077 - Inflammation vs. Immune-System Dysfunction in PCOS

September 18, 2026 · 28 min

For our 77th episode, we discuss a study in the Journal of Clinical Endocrinology & Metabolism investigating the role of immune signaling in polycystic ovary syndrome (PCOS), now renamed polyendocrine metabolic ovarian syndrome (PMOS)…
EFL076 - Pregnancy Outcomes in PCOS and GDM

August 25, 2026 · 47 min

For our 76th episode, we discuss a recent Journal of Clinical Endocrinology & Metabolism secondary analysis examining pregnancy outcomes among women with polycystic ovary syndrome (PCOS) and gestational diabetes mellitus (GDM). Drawing on…
EFL075 - Methimazole Titration and Initial Disease Severity in Graves' Disease

July 16, 2026 · 37 min

How does the severity of Graves disease at presentation affect subsequent methimazole dose titration? Find out more in this month's episode! For our 75th episode, we review a forthcoming Journal of Clinical Endocrinology & Metabolism study…
EFL074 - Taking Levothyroxine Fasting vs. With Breakfast

June 18, 2026 · 33 min

For our 74th episode, recorded live at ENDO 2026 in Chicago, we review a recent JCEM study that addresses a common clinical question: does levothyroxine need to be taken on an empty stomach? This randomized clinical trial evaluates a…
EFL073 - Infrequent Zoledronate in Low Fracture Risk

May 21, 2026 · 38 min

For our 73rd episode and the start of the seventh season, we review a recent study examining the long-term anti-fracture efficacy of infrequent zoledronate dosing in women with osteopenia. While current clinical approaches typically focus…

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EFL072 - Pre-Operative Use of Mineralocorticoid-Receptor Antagonists in Primary Aldosteronism

April 22, 2026 · 44 min

For our 72nd episode and the final episode of the sixth season, we review a recent study examining the perioperative medical management of primary aldosteronism, with a focus on the use of mineralocorticoid receptor antagonists before…
EFL071 – Taste Changes with Semaglutide

March 27, 2026 · 31 min

For our 71st episode, we review a randomized, placebo-controlled clinical trial that explores how semaglutide may influence taste perception in women with obesity and polycystic ovary syndrome. While GLP‑1 receptor agonists are widely used…
EFL070 – Dosing Strategies for Remission in Graves Disease

February 19, 2026 · 35 min

For our 70th episode, we review a paper that tries to improve our understanding of remission in Graves’ disease. Long-term thionamide treatment has long been the preferred approach internationally in Graves’ disease, and only more recently…
EFL069 - The Gut Microbiome in Type 1 Diabetes and Obesity

January 15, 2026 · 41 min

For our 69th episode, we review a paper in The Journal of Clinical Endocrinology & Metabolism on the gut microbiome of adolescents with type 1 diabetes, which hopes to understand differences between those with a normal body mass index…
EFL068 - Hypocalcemia in CKD after Denosumab

December 18, 2025 · 36 min

For our 68th episode, we look at a paper in The Journal of Clinical Endocrinology & Metabolism that compares the effect on calcium of initial and subsequent doses of denosumab in people with chronic kidney disease (CKD). Though concerns…
EFL067 - Bariatric Surgery and Changes in Body Composition and Musculoskeletal Health

November 20, 2025 · 43 min

For our 67th episode, we look at a study in The Journal of Clinical Endocrinology & Metabolism that reports the impact of different types of weight-loss surgery on body composition, muscle strength, and bone density. Our patients…
EFL066 - Islet Autoantibodies

October 16, 2025 · 36 min

For our 66th episode, we review a recent Journal of the Endocrine Society (JES) article that looks at the frequency of positive islet antibodies in a population of adults without diabetes. While that may initially seem like an unusual…

Full episode archive on Apple Podcasts →

About the show

Endocrine Feedback Loop is a monthly journal club podcast series brought to you by the Endocrine Society. Hosted by endocrinologist Chase Hendrickson, MD, from Vanderbilt University, each episode features an expert educator and a topical specialist dissecting recently published journal articles and discussing implications for clinical practice.