Science

Critical Matters

by Sound Physicians

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Latest episodes

Noninvasive Respiratory Support in Acute Respiratory Failure Patients

September 24, 2026 · 1 hr 3 min

Acute respiratory failure is one of the most common reasons adults require intensive care, and choosing the right respiratory support strategy can have a significant impact on patient outcomes. In this episode of Critical Matters, Dr…
Revisiting Hospital Sepsis Programs

September 10, 2026 · 1 hr 6 min

Sepsis remains one of the leading causes of death and disability worldwide, making early recognition and coordinated care essential to improving patient outcomes. In honor of Sepsis Awareness Month, observed every September, we are…
Communication with mechanically ventilated patients

August 27, 2026 · 58 min

For patients receiving mechanical ventilation, losing the ability to speak can be one of the most frightening and frustrating aspects of critical illness. In this episode of Critical Matters, Dr. Sergio Zanotti discusses the experience of…
Communicating to Patients and Families about PICS

August 13, 2026 · 1 hr 4 min

Recovering after a stay in the intensive care unit (ICU) is a long and difficult process, and for some survivors, healing the body may only be a fraction of the journey. In recent years, attention has increasingly turned to the cognitive…
Nutrition Therapy in the ICU

July 30, 2026 · 1 hr 8 min

When it comes to critical illness, nutrition isn't just supportive care—it can be a key part of the treatment plan. In this episode, Dr. Sergio Zanotti sits down with Dr. Jayshil Patel to discuss nutrition therapy for critically ill adults…

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Sepsis - Beyond the guidelines

July 9, 2026 · 54 min

In a recent episode, Dr. Sergio Zanotti discussed the 2026 iteration of the Surviving Sepsis Guidelines. In this episode, the discussion continues, focusing on important aspects beyond clinical guidelines. He is joined by Dr. Andre Kalil…
The Fearless ICU, revisited

June 25, 2026 · 51 min

This episode was originally posted Feb. 24, 2022. The last 24 months have pushed ICU teams around the world to their limits. As we move forward, we need to heal and rebuild our critical care teams. Healthcare more than ever will require…
Caring for older adults in the ICU

June 11, 2026 · 53 min

In this episode, Dr. Sergio Zanotti discusses the care of older adults in the ICU. He is joined by Dr. Lauren Ferrante, a pulmonary critical care physician in the medical intensive care unit at Yale New Haven Hospital. She is an Associate…
Rethinking arterial lines

May 28, 2026 · 41 min

In this episode, Dr. Sergio Zanotti discusses arterial catheters in shock through the lens of the recently published EVERDAC trial. He is joined by Dr. Gregoire Muller, a critical care physician in the Department of Intensive Care Medicine…
Invasive Candidiasis

May 14, 2026 · 57 min

In this, Dr. Sergio Zanotti discusses the management of invasive candidiasis in critically ill patients. Invasive candidiasis is frequent in critically ill patients and is associated with high mortality and morbidity. He is joined by Dr…
Surviving sepsis campaign 2026 guidelines

April 23, 2026 · 1 hr 12 min

In this episode, Dr. Zanotti discusses the Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026. He is joined by Dr. Hallie Prescot and Dr. Bram Rochwerg. Dr. Hallie Prescott is an Associate…
Management of Impella Emergencies

April 9, 2026 · 55 min

In this episode, Dr. Sergio Zanotti discusses emergency management and resuscitation of patients with left-sided Impella support. We will base our discussion on a recently published United Kingdom multisociety consensus statement. Our…